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YM750, an ACAT Inhibitor, Acts on Adrenocortical Cells to Inhibit Aldosterone Secretion Due to Depolarization

Primary aldosteronism (PA) is considered the most common form of secondary hypertension, which is associated with excessive aldosterone secretion in the adrenal cortex. The cause of excessive aldosterone secretion is the induction of aldosterone synthase gene (CYP11B2) expression by depolarization o...

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Detalles Bibliográficos
Autores principales: Shimada, Hiroki, Hata, Shuko, Yamazaki, Yuto, Otsubo, Yuri, Sato, Ikuko, Ise, Kazue, Yokoyama, Atsushi, Suzuki, Takashi, Sasano, Hironobu, Sugawara, Akira, Nakamura, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655524/
https://www.ncbi.nlm.nih.gov/pubmed/36361592
http://dx.doi.org/10.3390/ijms232112803