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YM750, an ACAT Inhibitor, Acts on Adrenocortical Cells to Inhibit Aldosterone Secretion Due to Depolarization
Primary aldosteronism (PA) is considered the most common form of secondary hypertension, which is associated with excessive aldosterone secretion in the adrenal cortex. The cause of excessive aldosterone secretion is the induction of aldosterone synthase gene (CYP11B2) expression by depolarization o...
Autores principales: | Shimada, Hiroki, Hata, Shuko, Yamazaki, Yuto, Otsubo, Yuri, Sato, Ikuko, Ise, Kazue, Yokoyama, Atsushi, Suzuki, Takashi, Sasano, Hironobu, Sugawara, Akira, Nakamura, Yasuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655524/ https://www.ncbi.nlm.nih.gov/pubmed/36361592 http://dx.doi.org/10.3390/ijms232112803 |
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