Apelin-13 Increases Functional Connexin-43 through Autophagy Inhibition via AKT/mTOR Pathway in the Non-Myocytic Cell Population of the Heart

Studies have shown a link between the downregulation of connexin 43 (Cx43), the predominant isoform in cardiac gap junctions, and high susceptibility to cardiac arrhythmias and cardiomyocyte death. Non-myocytic cells (NMCs), the most abundant component of the heart, exert multiple cardiac functions...

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Detalles Bibliográficos
Autores principales: Vitale, Emanuela, Rosso, Rachele, Lo Iacono, Marco, Cristallini, Caterina, Giachino, Claudia, Rastaldo, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655608/
https://www.ncbi.nlm.nih.gov/pubmed/36361860
http://dx.doi.org/10.3390/ijms232113073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655608/
https://www.ncbi.nlm.nih.gov/pubmed/36361860
http://dx.doi.org/10.3390/ijms232113073

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