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L-Type Ca(2+) Channel Inhibition Rescues the LPS-Induced Neuroinflammatory Response and Impairments in Spatial Memory and Dendritic Spine Formation

Ca(2+) signaling is implicated in the transition between microglial surveillance and activation. Several L-type Ca(2+) channel blockers (CCBs) have been shown to ameliorate neuroinflammation by modulating microglial activity. In this study, we examined the effects of the L-type CCB felodipine on LPS...

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Detalles Bibliográficos
Autores principales: Kim, Jieun, Jeon, Seong Gak, Jeong, Ha-Ram, Park, HyunHee, Kim, Jae-Ick, Hoe, Hyang-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655622/
https://www.ncbi.nlm.nih.gov/pubmed/36362394
http://dx.doi.org/10.3390/ijms232113606