Repeated Administration of Cisplatin Transforms Kidney Fibroblasts through G2/M Arrest and Cellular Senescence

Cisplatin is a potent chemotherapeutic used for the treatment of many types of cancer, but it has nephrotoxic side effects leading to acute kidney injury and subsequently chronic kidney disease (CKD). Previous work has focused on acute kidney tubular injury induced by cisplatin, whereas the chronic...

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Detalles Bibliográficos
Autores principales: Yu, Jia-Bin, Lee, Dong-Sun, Padanilam, Babu J., Kim, Jinu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655665/
https://www.ncbi.nlm.nih.gov/pubmed/36359868
http://dx.doi.org/10.3390/cells11213472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655665/
https://www.ncbi.nlm.nih.gov/pubmed/36359868
http://dx.doi.org/10.3390/cells11213472

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