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Repeated Administration of Cisplatin Transforms Kidney Fibroblasts through G2/M Arrest and Cellular Senescence
Cisplatin is a potent chemotherapeutic used for the treatment of many types of cancer, but it has nephrotoxic side effects leading to acute kidney injury and subsequently chronic kidney disease (CKD). Previous work has focused on acute kidney tubular injury induced by cisplatin, whereas the chronic...
Autores principales: | Yu, Jia-Bin, Lee, Dong-Sun, Padanilam, Babu J., Kim, Jinu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655665/ https://www.ncbi.nlm.nih.gov/pubmed/36359868 http://dx.doi.org/10.3390/cells11213472 |
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