Recognition of a Clickable Abasic Site Analog by DNA Polymerases and DNA Repair Enzymes

Azide–alkyne cycloaddition (“click chemistry”) has found wide use in the analysis of molecular interactions in living cells. 5-ethynyl-2-(hydroxymethyl)tetrahydrofuran-3-ol (EAP) is a recently developed apurinic/apyrimidinic (AP) site analog functionalized with an ethynyl moiety, which can be introd...

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Detalles Bibliográficos
Autores principales: Endutkin, Anton V., Yudkina, Anna V., Zharkov, Timofey D., Kim, Daria V., Zharkov, Dmitry O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655677/
https://www.ncbi.nlm.nih.gov/pubmed/36362137
http://dx.doi.org/10.3390/ijms232113353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655677/
https://www.ncbi.nlm.nih.gov/pubmed/36362137
http://dx.doi.org/10.3390/ijms232113353

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