Trichostatin A-Mediated Epigenetic Modulation Predominantly Triggers Transcriptomic Alterations in the Ex Vivo Expanded Equine Chondrocytes

Epigenetic mechanisms of gene regulation are important for the proper differentiation of cells used for therapeutic and regenerative purposes. The primary goal of the present study was to investigate the impacts of 5-aza-2′ deoxycytidine (5-AZA-dc)- and/or trichostatin A (TSA)-mediated approaches ap...

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Detalles Bibliográficos
Autores principales: Ząbek, Tomasz, Witarski, Wojciech, Szmatoła, Tomasz, Sawicki, Sebastian, Mrozowicz, Justyna, Samiec, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655705/
https://www.ncbi.nlm.nih.gov/pubmed/36361948
http://dx.doi.org/10.3390/ijms232113168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655705/
https://www.ncbi.nlm.nih.gov/pubmed/36361948
http://dx.doi.org/10.3390/ijms232113168

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