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Small Heterocyclic Ligands as Anticancer Agents: QSAR with a Model G-Quadruplex

G-quadruplexes (GQs) have become valid targets for anticancer studies in recent decades due to their multifaceted biological function. Herewith, we aim to quantify interactions of potential heterocyclic ligands (Ls) with model GQs. For seven 4-aminoquinazolines and three 2-heteroaryl perimidines, se...

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Detalles Bibliográficos
Autores principales: Kaneti, Jose, Kurteva, Vanya, Georgieva, Milena, Krasteva, Natalia, Miloshev, George, Tabakova, Nadezhda, Petkova, Zhanina, Bakalova, Snezhana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655707/
https://www.ncbi.nlm.nih.gov/pubmed/36364401
http://dx.doi.org/10.3390/molecules27217577