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Differential Effects of Human Tau Isoforms to Neuronal Dysfunction and Toxicity in the Drosophila CNS

Accumulation of highly post-translationally modified tau proteins is a hallmark of neurodegenerative disorders known as tauopathies, the most common of which is Alzheimer’s disease. Although six tau isoforms are found in the human brain, the majority of animal and cellular tauopathy models utilize a...

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Detalles Bibliográficos
Autores principales: Vourkou, Ergina, Paspaliaris, Vassilis, Bourouliti, Anna, Zerva, Maria-Christina, Prifti, Engie, Papanikolopoulou, Katerina, Skoulakis, Efthimios M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655709/
https://www.ncbi.nlm.nih.gov/pubmed/36361774
http://dx.doi.org/10.3390/ijms232112985