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Curcumin Reprograms TAMs from a Protumor Phenotype towards an Antitumor Phenotype via Inhibiting MAO-A/STAT6 Pathway

M1 phenotype macrophages have anticancer characteristics, whereas M2 phenotype macrophages promote tumor growth and metastasis. A higher M1/M2 ratio, therefore, has a beneficial effect on the tumor immune microenvironment, thereby inhibiting tumor growth. The natural alkaloid curcumin is found to ha...

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Detalles Bibliográficos
Autores principales: Jiang, Mingjing, Qi, Ying, Huang, Wei, Lin, Ying, Li, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655729/
https://www.ncbi.nlm.nih.gov/pubmed/36359867
http://dx.doi.org/10.3390/cells11213473