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The Crystal Structure of Mouse Ces2c, a Potential Ortholog of Human CES2, Shows Structural Similarities in Substrate Regulation and Product Release to Human CES1

Members of the carboxylesterase 2 (Ces2/CES2) family have been studied intensively with respect to their hydrolytic function on (pro)drugs, whereas their physiological role in lipid and energy metabolism has been realized only within the last few years. Humans have one CES2 gene which is highly expr...

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Detalles Bibliográficos
Autores principales: Eisner, Helgit, Riegler-Berket, Lina, Gamez, Carlos Francisco Rodriguez, Sagmeister, Theo, Chalhoub, Gabriel, Darnhofer, Barbara, Jazleena, P J, Birner-Gruenberger, Ruth, Pavkov-Keller, Tea, Haemmerle, Guenter, Schoiswohl, Gabriele, Oberer, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655854/
https://www.ncbi.nlm.nih.gov/pubmed/36361897
http://dx.doi.org/10.3390/ijms232113101