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Novel Hydroxypyridine Compound Protects Brain Cells against Ischemic Damage In Vitro and In Vivo

A non-surgical pharmacological approach to control cellular vitality and functionality during ischemic and/or reperfusion-induced phases of strokes remains extremely important. The synthesis of 2-ethyl-6-methyl-3-hydroxypyridinium gammalactone-2,3-dehydro-L-gulonate (3-EA) was performed using a topo...

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Detalles Bibliográficos
Autores principales: Blinova, Ekaterina, Turovsky, Egor, Eliseikina, Elena, Igrunkova, Alexandra, Semeleva, Elena, Golodnev, Grigorii, Termulaeva, Rita, Vasilkina, Olga, Skachilova, Sofia, Mazov, Yan, Zhandarov, Kirill, Simakina, Ekaterina, Belanov, Konstantin, Zalogin, Saveliy, Blinov, Dmitrii
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655885/
https://www.ncbi.nlm.nih.gov/pubmed/36361739
http://dx.doi.org/10.3390/ijms232112953