Inhibition of Netosis with PAD Inhibitor Attenuates Endotoxin Shock Induced Systemic Inflammation

Neutrophils play a pivotal role in innate immunity by releasing neutrophils extracellular traps (NETs). Excessive NETs are detrimental to the local tissue and further exacerbate inflammation. Protein arginine deiminases (PAD) mediate histone citrullination and NET formation that, in turn, exacerbate...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Huanling, Cao, Guojie, Liu, Zheng, Zhao, Yue, Yan, Zhanchao, Wang, Senzhen, Wang, Yuehua, Guo, Zhengwei, Wang, Yanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655899/
https://www.ncbi.nlm.nih.gov/pubmed/36362052
http://dx.doi.org/10.3390/ijms232113264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655899/
https://www.ncbi.nlm.nih.gov/pubmed/36362052
http://dx.doi.org/10.3390/ijms232113264

Ejemplares similares