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Synthesis, characterization, and cytotoxicity of doxorubicin-loaded polycaprolactone nanocapsules as controlled anti-hepatocellular carcinoma drug release system

BACKGROUND: Free doxorubicin (Dox) is used as a chemotherapeutic agent against hepatocellular carcinoma (HCC), but it results in cardiotoxicty as a major side effect. Hence, a controlled Dox drug delivery system is extremely demanded. METHODS: Dox was loaded into the non-toxic biodegradable polycapr...

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Detalles Bibliográficos
Autores principales: Fahmi, Abdelgawad, Abdur-Rahman, Mariam, Mahareek, Omnia, shemis, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655909/
https://www.ncbi.nlm.nih.gov/pubmed/36371274
http://dx.doi.org/10.1186/s13065-022-00888-w