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2,4-Dinitrophenol as an Uncoupler Augments the Anthracyclines Toxicity against Prostate Cancer Cells

One of the strategies for the treatment of advanced cancer diseases is targeting the energy metabolism of the cancer cells. The compound 2,4-DNP (2,4-dinitrophenol) disrupts the cell energy metabolism through the ability to decouple oxidative phosphorylation. The aim of the study was to determine th...

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Detalles Bibliográficos
Autores principales: Adamczuk, Grzegorz, Humeniuk, Ewelina, Adamczuk, Kamila, Grabarska, Aneta, Dudka, Jarosław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655928/
https://www.ncbi.nlm.nih.gov/pubmed/36364051
http://dx.doi.org/10.3390/molecules27217227