Cargando…

2,4-Dinitrophenol as an Uncoupler Augments the Anthracyclines Toxicity against Prostate Cancer Cells

One of the strategies for the treatment of advanced cancer diseases is targeting the energy metabolism of the cancer cells. The compound 2,4-DNP (2,4-dinitrophenol) disrupts the cell energy metabolism through the ability to decouple oxidative phosphorylation. The aim of the study was to determine th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Adamczuk, Grzegorz, Humeniuk, Ewelina, Adamczuk, Kamila, Grabarska, Aneta, Dudka, Jarosław
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655928/ https://www.ncbi.nlm.nih.gov/pubmed/36364051 http://dx.doi.org/10.3390/molecules27217227

Ejemplares similares

Apigenin and Hesperidin Downregulate DNA Repair Genes in MCF-7 Breast Cancer Cells and Augment Doxorubicin Toxicity
por: Korga-Plewko, Agnieszka, et al.
Publicado: (2020)

Cardioprotective Effect of Centaurea castriferrei Borbás & Waisb Extract against Doxorubicin-Induced Cardiotoxicity in H9c2 Cells
por: Humeniuk, Ewelina, et al.
Publicado: (2023)

Cytotoxic activity of methanolic fractions of different Marrubium spp. against melanoma cells is independent of antioxidant activity and total phenolic content
por: Kozyra, Malgorzata, et al.
Publicado: (2019)

The Mitochondria-Independent Cytotoxic Effect of Leflunomide on RPMI-8226 Multiple Myeloma Cell Line
por: Adamczuk, Grzegorz, et al.
Publicado: (2021)

Phytochemical Analysis and Anti-Cancer Properties of Extracts of Centaurea castriferrei Borbás & Waisb Genus of Centaurea L
por: Kubik, Joanna, et al.
Publicado: (2022)

Hyaluronic Acid as a Modern Approach in Anticancer Therapy-Review
por: Michalczyk, Monika, et al.
Publicado: (2022)

2,4 Dinitrophenol as Medicine
por: Geisler, John G.
Publicado: (2019)

Targeting Energy Metabolism in Cancer Treatment
por: Kubik, Joanna, et al.
Publicado: (2022)

Sublethal toxicities of 2,4-dinitrophenol as inferred from online self-reports
por: Abdelati, Ali, et al.
Publicado: (2023)

Mitochondrial Uncoupler Prodrug of 2,4-Dinitrophenol, MP201, Prevents Neuronal Damage and Preserves Vision in Experimental Optic Neuritis
por: Khan, Reas S., et al.
Publicado: (2017)

Neuroprotective actions of 2,4-dinitrophenol: Friend or foe?
por: Ferreira, Sérgio Teixeira, et al.
Publicado: (2007)

Palmatine, a Bioactive Protoberberine Alkaloid Isolated from Berberis cretica, Inhibits the Growth of Human Estrogen Receptor-Positive Breast Cancer Cells and Acts Synergistically and Additively with Doxorubicin
por: Grabarska, Aneta, et al.
Publicado: (2021)

Deacetylation of Transcription Factors in Carcinogenesis
por: Halasa, Marta, et al.
Publicado: (2021)

Synthesis and Evaluation of a Molecularly Imprinted Polymer for 2,4-Dinitrophenol
por: Zakaria, Nor Dyana, et al.
Publicado: (2009)

2-Hydroxyethanaminium 2,4-dinitrophenolate hemihydrate
por: Yan, Yong, et al.
Publicado: (2010)

Influence of Complexation of Thiosemicarbazone Derivatives with Cu (II) Ions on Their Antitumor Activity against Melanoma Cells
por: Pitucha, Monika, et al.
Publicado: (2021)

Impact of Chitosan on the Mechanical Stability of Soils
por: Adamczuk, Agnieszka, et al.
Publicado: (2022)

Synthesis and Characterization of Molecularly Imprinted Polymer Membrane for the Removal of 2,4-Dinitrophenol
por: Yusof, Nor Azah, et al.
Publicado: (2013)

Biodegradation of 2,4-dinitrophenol with laccase immobilized on nano-porous silica beads
por: Dehghanifard, Emad, et al.
Publicado: (2013)

Light affects in vitro organogenesis of Linum usitatissimum L. and its cyanogenic potential
por: Siegień, Irena, et al.
Publicado: (2012)

Heterogeneous Cellular Response of Primary and Metastatic Human Gastric Adenocarcinoma Cell Lines to Magnoflorine and Its Additive Interaction with Docetaxel
por: Grabarska, Aneta, et al.
Publicado: (2023)

Mitochondrial Uncoupling Proteins (UCP1-UCP3) and Adenine Nucleotide Translocase (ANT1) Enhance the Protonophoric Action of 2,4-Dinitrophenol in Mitochondria and Planar Bilayer Membranes
por: Žuna, Kristina, et al.
Publicado: (2021)

Apigenin and hesperidin augment the toxic effect of doxorubicin against HepG2 cells
por: Korga, Agnieszka, et al.
Publicado: (2019)

Effects of Caffeine on Metabolism and Mitochondria Biogenesis in Rhabdomyosarcoma Cells Compared with 2,4-Dinitrophenol
por: Vaughan, Roger A., et al.
Publicado: (2012)

Arsenate Adsorption on Fly Ash, Chitosan and Their Composites and Its Relations with Surface, Charge and Pore Properties of the Sorbents
por: Adamczuk, Agnieszka, et al.
Publicado: (2020)

The Failure of Dinitrophenol to Influence the Vitamin B Requirement
por: Cowgill, George R., et al.
Publicado: (1936)

4-Chloro-2,6-dinitrophenol
por: Ng, Seik Weng
Publicado: (2010)

In Situ Stabilisation of Silver Nanoparticles at Chitosan-Functionalised Graphene Oxide for Reduction of 2,4-Dinitrophenol in Water
por: Makaudi, Rebaone, et al.
Publicado: (2021)

Impact of Chitosan on Water Stability and Wettability of Soils
por: Adamczuk, Agnieszka, et al.
Publicado: (2021)

FSHR Trans-Activation and Oligomerization
por: Szymańska, Kamila, et al.
Publicado: (2018)

Body Mass Parameters, Lipid Profiles and Protein Contents of Zebrafish Embryos and Effects of 2,4-Dinitrophenol Exposure
por: Hachicho, Nancy, et al.
Publicado: (2015)

Liposomal Form of 2,4-Dinitrophenol Lipophilic Derivatives as a Promising Therapeutic Agent for ATP Synthesis Inhibition
por: Vlasova, Kseniya Yu., et al.
Publicado: (2022)

THE EFFECT OF DINITROPHENOL AND THYROXIN ON THE SUSCEPTIBILITY OF MICE TO STAPHYLOCOCCAL INFECTIONS
por: Smiths, J. Maclean, et al.
Publicado: (1956)

Ionization Constants of Four Dinitrophenols in Water at 25 °C
por: Robinson, Robert A., et al.
Publicado: (1960)

Matching Minute Ventilation in Hypermetabolic State of Dinitrophenol Poisoning
por: Hendrickson, Kathryn, et al.
Publicado: (2020)

Effect of Low Zeolite Doses on Plants and Soil Physicochemical Properties
por: Szatanik-Kloc, Alicja, et al.
Publicado: (2021)

Would You Use It With a Seal of Approval? Important Attributes of 2,4-Dinitrophenol (2,4-DNP) as a Hypothetical Pharmaceutical Product
por: Bleasdale, Emma E., et al.
Publicado: (2018)

Genome-based insights into the resistome and mobilome of multidrug-resistant Aeromonas sp. ARM81 isolated from wastewater
por: Adamczuk, Marcin, et al.
Publicado: (2016)

β-Cyclodextrin conjugated bifunctional isocyanate linker polymer for enhanced removal of 2,4-dinitrophenol from environmental waters
por: Anne, J. M., et al.
Publicado: (2018)

Mono and co-immobilization of imidazolium ionic liquids on silica: effects of the substituted groups on the adsorption behavior of 2,4-dinitrophenol
por: Wang, Zhike, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_jmida6friueti1c0uut6q5msuv