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Emerging Role of miR-21-5p in Neuron–Glia Dysregulation and Exosome Transfer Using Multiple Models of Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative disorder associated with neuron–glia dysfunction and dysregulated miRNAs. We previously reported upregulated miR-124/miR-21 in AD neurons and their exosomes. However, their glial distribution, phenotypic alterations and exosomal spread are scarcely doc...

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Detalles Bibliográficos
Autores principales: Garcia, Gonçalo, Pinto, Sara, Ferreira, Sofia, Lopes, Daniela, Serrador, Maria João, Fernandes, Adelaide, Vaz, Ana Rita, de Mendonça, Alexandre, Edenhofer, Frank, Malm, Tarja, Koistinaho, Jari, Brites, Dora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655962/
https://www.ncbi.nlm.nih.gov/pubmed/36359774
http://dx.doi.org/10.3390/cells11213377