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Emerging Role of miR-21-5p in Neuron–Glia Dysregulation and Exosome Transfer Using Multiple Models of Alzheimer’s Disease
Alzheimer’s disease (AD) is a neurodegenerative disorder associated with neuron–glia dysfunction and dysregulated miRNAs. We previously reported upregulated miR-124/miR-21 in AD neurons and their exosomes. However, their glial distribution, phenotypic alterations and exosomal spread are scarcely doc...
Autores principales: | Garcia, Gonçalo, Pinto, Sara, Ferreira, Sofia, Lopes, Daniela, Serrador, Maria João, Fernandes, Adelaide, Vaz, Ana Rita, de Mendonça, Alexandre, Edenhofer, Frank, Malm, Tarja, Koistinaho, Jari, Brites, Dora |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655962/ https://www.ncbi.nlm.nih.gov/pubmed/36359774 http://dx.doi.org/10.3390/cells11213377 |
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