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ERK Inhibition Increases RANKL-Induced Osteoclast Differentiation in RAW 264.7 Cells by Stimulating AMPK Activation and RANK Expression and Inhibiting Anti-Osteoclastogenic Factor Expression

Bone absorption is necessary for the maintenance of bone homeostasis. An osteoclast (OC) is a monocyte–macrophage lineage cell that absorbs bone tissue. Extracellular signal-regulated kinases (ERKs) are known to play important roles in regulating OC growth and differentiation. In this study, we exam...

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Detalles Bibliográficos
Autores principales: Choi, Eun-Bi, Agidigbi, Taiwo Samuel, Kang, In-Soon, Kim, Chaekyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656104/
https://www.ncbi.nlm.nih.gov/pubmed/36362318
http://dx.doi.org/10.3390/ijms232113512