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Oligomerization of Human Cystatin C—An Amyloidogenic Protein: An Analysis of Small Oligomeric Subspecies

Human cystatin C (HCC), an amyloidogenic protein, forms dimers and higher oligomers (trimers, tetramers and donut like large oligomers) via a domain-swapping mechanism. The aim of this study was the characterization of the HCC oligomeric states observed within the pH range from 2.2 to 10.0 and also...

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Detalles Bibliográficos
Autores principales: Wojciechowska, Daria, Taube, Michał, Rucińska, Karolina, Maksim, Joanna, Kozak, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656228/
https://www.ncbi.nlm.nih.gov/pubmed/36362228
http://dx.doi.org/10.3390/ijms232113441