From Differential DNA Methylation in COPD to Mitochondria: Regulation of AHRR Expression Affects Airway Epithelial Response to Cigarette Smoke

Cigarette smoking causes hypomethylation of the gene Aryl Hydrocarbon Receptor Repressor (AHRR), which regulates detoxification and oxidative stress-responses. We investigated whether AHRR DNA methylation is related to chronic obstructive pulmonary disease (COPD) and studied its function in airway e...

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Detalles Bibliográficos
Autores principales: Chen, Qing, Nwozor, Kingsley Okechukwu, van den Berge, Maarten, Slebos, Dirk-Jan, Faiz, Alen, Jonker, Marnix R., Boezen, H. Marike, Heijink, Irene H., de Vries, Maaike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656229/
https://www.ncbi.nlm.nih.gov/pubmed/36359818
http://dx.doi.org/10.3390/cells11213423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656229/
https://www.ncbi.nlm.nih.gov/pubmed/36359818
http://dx.doi.org/10.3390/cells11213423

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