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A Pyrazolate Osmium(VI) Nitride Exhibits Anticancer Activity through Modulating Protein Homeostasis in HepG2 Cells

Interest in the third-row transition metal osmium and its compounds as potential anticancer agents has grown in recent years. Here, we synthesized the osmium(VI) nitrido complex Na[Os(VI)(N)(tpm)(2)] (tpm = [5-(Thien-2-yl)-1H-pyrazol-3-yl]methanol), which exhibited a greater inhibitory effect on the...

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Detalles Bibliográficos
Autores principales: Huang, Chengyang, Huang, Wanqiong, Ji, Pengchao, Song, Fuling, Liu, Tao, Li, Meiyang, Guo, Hongzhi, Huang, Yongliang, Yu, Cuicui, Wang, Chuanxian, Ni, Wenxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656236/
https://www.ncbi.nlm.nih.gov/pubmed/36361570
http://dx.doi.org/10.3390/ijms232112779