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Ethyl Methane Sulfonate and Sodium Azide-Mediated Chemical and X-ray-Mediated Physical Mutagenesis Positively Regulate Peroxidase 1 Gene Activity and Biosynthesis of Antineoplastic Vinblastine in Catharanthus roseus

Catharanthus roseus synthesizes bioactive therapeutic metabolites, known as monoterpenoid indole alkaloids (MIAs), including antineoplastic vinblastine and vincristine, which have high global demand, and antihypertensive ajmalicine, a serpentine. However, the in planta biosynthesis and accumulation...

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Detalles Bibliográficos
Autores principales: Mistry, Vyoma, Tiwari, Pragya, Patel, Paresh, Vishwakarma, Gajendra Singh, Lee, Geung-Joo, Sharma, Abhishek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656251/
https://www.ncbi.nlm.nih.gov/pubmed/36365340
http://dx.doi.org/10.3390/plants11212885