Cargando…

Cardioprotection by Hypothyroidism Is Not Mediated by Favorable Hemodynamics—Role of Canonical Thyroid Hormone Receptor Alpha Signaling

Hypothyroidism has been shown to reduce infarct size in rats, but the underlying mechanisms are unclear. We used isolated pressure-constant perfused hearts of control, hypothyroid and hyperthyroid mice and measured infarct size, functional parameters and phosphorylation of key molecules in cardiopro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pape, Janina, Kerp, Helena, Lieder, Helmut R., Geist, Daniela, Hönes, Georg Sebastian, Moeller, Lars C., Kleinbongard, Petra, Führer, Dagmar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656281/ https://www.ncbi.nlm.nih.gov/pubmed/36362133 http://dx.doi.org/10.3390/ijms232113340

Ejemplares similares

Protective Effects of Thyroid Hormone Deprivation on Progression of Maladaptive Cardiac Hypertrophy and Heart Failure
por: Kerp, Helena, et al.
Publicado: (2021)

Diazoxide is a powerful cardioprotectant but is not feasible in a realistic infarct scenario
por: Kleinbongard, Petra, et al.
Publicado: (2023)

Sex-specific phenotypes of hyperthyroidism and hypothyroidism in aged mice
por: Rakov, Helena, et al.
Publicado: (2017)

Sex is no determinant of cardioprotection by ischemic preconditioning in rats, but ischemic/reperfused tissue mass is for remote ischemic preconditioning
por: Lieder, Helmut R., et al.
Publicado: (2019)

Sex-specific phenotypes of hyperthyroidism and hypothyroidism in mice
por: Rakov, Helena, et al.
Publicado: (2016)

Platelet-Mediated Transfer of Cardioprotection by Remote Ischemic Conditioning and Its Abrogation by Aspirin But Not by Ticagrelor
por: Lieder, Helmut Raphael, et al.
Publicado: (2022)

Cardioprotection by post-conditioning with exogenous triiodothyronine in isolated perfused rat hearts and isolated adult rat cardiomyocytes
por: Lieder, Helmut Raphael, et al.
Publicado: (2021)

Non-responsiveness to cardioprotection by ischaemic preconditioning in Ossabaw minipigs with genetic predisposition to, but without the phenotype of the metabolic syndrome
por: Kleinbongard, Petra, et al.
Publicado: (2022)

Perspective: mitochondrial STAT3 in cardioprotection
por: Kleinbongard, Petra
Publicado: (2023)

Tentative Application of a Streamlined Protocol to Determine Organ-Specific Regulations of Deiodinase 1 and Dehalogenase Activities as Readouts of the Hypothalamus-Pituitary-Thyroid-Periphery-Axis
por: Renko, Kostja, et al.
Publicado: (2022)

Cardioprotection by early metoprolol- attenuation of ischemic vs. reperfusion injury?
por: Kleinbongard, Petra
Publicado: (2020)

Aspirate from human stented saphenous vein grafts induces epicardial coronary vasoconstriction and impairs perfusion and left ventricular function in rat bioassay hearts with pharmacologically induced endothelial dysfunction
por: Lieder, Helmut R., et al.
Publicado: (2016)

No robust reduction of infarct size and no-reflow by metoprolol pretreatment in adult Göttingen minipigs
por: Kleinbongard, Petra, et al.
Publicado: (2023)

Cell-Specific Transport and Thyroid Hormone Receptor Isoform Selectivity Account for Hepatocyte-Targeted Thyromimetic Action of MGL-3196
por: Hönes, Georg Sebastian, et al.
Publicado: (2022)

Canonical and Non-Canonical Roles of Connexin43 in Cardioprotection
por: Rusiecka, Olga M., et al.
Publicado: (2020)

Co‐morbidities and co‐medications as confounders of cardioprotection—Does it matter in the clinical setting?
por: Kleinbongard, Petra, et al.
Publicado: (2020)

Functional Characterization of Olfactory Receptors in the Thyroid Gland
por: Weidinger, Daniel, et al.
Publicado: (2021)

Is dexmedetomidine a favorable agent for cerebral hemodynamics?
por: Tsaousi, Georgia G., et al.
Publicado: (2016)

Acute hemodynamic effects of erythropoietin do not mediate its cardioprotective properties
por: Ahmet, Ismayil, et al.
Publicado: (2012)

Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain
por: Remaud, Sylvie, et al.
Publicado: (2017)

TWEAK favors phosphate-induced calcification of vascular smooth muscle cells through canonical and non-canonical activation of NFκB
por: Hénaut, L, et al.
Publicado: (2016)

Canonical and Non-canonical Reelin Signaling
por: Bock, Hans H., et al.
Publicado: (2016)

Endothelial Functioning and Hemodynamic Parameters in Rats with Subclinical Hypothyroid and the Effects of Thyroxine Replacement
por: Gao, Cuixia, et al.
Publicado: (2015)

Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection
por: Bøtker, Hans Erik, et al.
Publicado: (2018)

Effects of Ischemic Postconditioning on the Hemodynamic Parameters and Heart Nitric Oxide Levels of Hypothyroid Rats
por: Jeddi, Sajad, et al.
Publicado: (2015)

SAT-511 Alpha Gal Allergy in a Hypothyroid Patient
por: Slayden, Tanner A, et al.
Publicado: (2020)

The Cardioprotective Effect of Vitamin E (Alpha-Tocopherol) Is Strongly Related to Age and Gender in Mice
por: Hu, Xiao-Xia, et al.
Publicado: (2015)

A fresh look at coronary microembolization
por: Kleinbongard, Petra, et al.
Publicado: (2021)

Países escandinavos
por: Kerp, Heinrich. 1864-
Publicado: (1930)

A High-Protein and Low-Glycemic Formula Diet Improves Blood Pressure and Other Hemodynamic Parameters in High-Risk Individuals
por: Röhling, Martin, et al.
Publicado: (2022)

Adolescent with Rhabdomyolysis due to Undiagnosed Hypothyroidism
por: Farias Moeller, Raquel, et al.
Publicado: (2011)

Antibodies targeting conserved non-canonical antigens and endemic coronaviruses associate with favorable outcomes in severe COVID-19
por: Peddireddy, Sai Preetham, et al.
Publicado: (2022)

Cardioprotection and ageing
por: Shim, Yon Hee
Publicado: (2010)

Telmisartan and cardioprotection
por: Akhrass, Philippe R, et al.
Publicado: (2011)

Perioperative cardioprotection
por: Leung, May KM, et al.
Publicado: (2013)

Mitophagy for cardioprotection
por: Titus, Allen Sam, et al.
Publicado: (2023)

Ultraviolet irradiation doses for coronavirus inactivation – review and analysis of coronavirus photoinactivation studies
por: Heßling, Martin, et al.
Publicado: (2020)

Six canonic sontas : for two violins
por: Telemann, Georg Philipp, 1681-1767

Non-Canonical Mechanisms Regulating Hypoxia-Inducible Factor 1 Alpha in Cancer
por: Iommarini, Luisa, et al.
Publicado: (2017)

The platelet paradox of injury versus protection in myocardial infarction—has it been overlooked?
por: Kleinbongard, Petra, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2eggrs8m3hg3nokridth6qflop