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KRAS in NSCLC: State of the Art and Future Perspectives

SIMPLE SUMMARY: Rat sarcoma virus (RAS) GTP-ase proteins represent a key element in cellular proliferation, growth, and differentiation. Three different isoforms of RAS proteins have been identified to date (KRAS, NRAS, HRAS) and mutations in KRAS are frequently found in human cancers, among which t...

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Detalles Bibliográficos
Autores principales: Cascetta, Priscilla, Marinello, Arianna, Lazzari, Chiara, Gregorc, Vanesa, Planchard, David, Bianco, Roberto, Normanno, Nicola, Morabito, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656434/
https://www.ncbi.nlm.nih.gov/pubmed/36358848
http://dx.doi.org/10.3390/cancers14215430