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Spermidine/Spermine N1-Acetyltransferase 1 (SAT1)—A Potential Gene Target for Selective Sensitization of Glioblastoma Cells Using an Ionizable Lipid Nanoparticle to Deliver siRNA

SIMPLE SUMMARY: Glioblastoma (GB) is an aggressive form of brain cancer with no effective cure. The current treatment for GB involves surgical removal of the tumor followed by chemotherapy and radiation therapy. However, GB develops chemo and radiation therapy resistance, leading to tumor recurrence...

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Detalles Bibliográficos
Autores principales: Yathindranath, Vinith, Safa, Nura, Sajesh, Babu V., Schwinghamer, Kelly, Vanan, Magimairajan Issai, Bux, Rashid, Sitar, Daniel S., Pitz, Marshall, Siahaan, Teruna J., Miller, Donald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656607/
https://www.ncbi.nlm.nih.gov/pubmed/36358597
http://dx.doi.org/10.3390/cancers14215179