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Spermidine/Spermine N1-Acetyltransferase 1 (SAT1)—A Potential Gene Target for Selective Sensitization of Glioblastoma Cells Using an Ionizable Lipid Nanoparticle to Deliver siRNA
SIMPLE SUMMARY: Glioblastoma (GB) is an aggressive form of brain cancer with no effective cure. The current treatment for GB involves surgical removal of the tumor followed by chemotherapy and radiation therapy. However, GB develops chemo and radiation therapy resistance, leading to tumor recurrence...
Autores principales: | Yathindranath, Vinith, Safa, Nura, Sajesh, Babu V., Schwinghamer, Kelly, Vanan, Magimairajan Issai, Bux, Rashid, Sitar, Daniel S., Pitz, Marshall, Siahaan, Teruna J., Miller, Donald W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656607/ https://www.ncbi.nlm.nih.gov/pubmed/36358597 http://dx.doi.org/10.3390/cancers14215179 |
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