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Enhanced Cardiorenal Protective Effects of Combining SGLT2 Inhibition, Endothelin Receptor Antagonism and RAS Blockade in Type 2 Diabetic Mice

Treatments with sodium–glucose 2 cotransporter inhibitors (SGLT2i) or endothelin receptor antagonists (ERA) have shown cardiorenal protective effects. The present study aimed to evaluate the cardiorenal beneficial effects of the combination of SGLT2i and ERA on top of renin–angiotensin system (RAS)...

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Detalles Bibliográficos
Autores principales: Vergara, Ander, Jacobs-Cacha, Conxita, Llorens-Cebria, Carmen, Ortiz, Alberto, Martinez-Diaz, Irene, Martos, Nerea, Dominguez-Báez, Pamela, Van den Bosch, Mireia Molina, Bermejo, Sheila, Pieper, Michael Paul, Benito, Begoña, Soler, Maria Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656616/
https://www.ncbi.nlm.nih.gov/pubmed/36361612
http://dx.doi.org/10.3390/ijms232112823