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Antifibrotic TSG-6 Expression Is Synergistically Increased in Both Cells during Coculture of Mesenchymal Stem Cells and Macrophages via the JAK/STAT Signaling Pathway

The pro-inflammatory cytokines tumor necrosis factor-alpha (TNF-α) and interleukin (IL)-1β upregulate TNF-α-stimulated gene 6 (TSG-6); however, current knowledge about the optimal conditions for TSG-6 expression in mesenchymal stem cells (MSCs) is limited. Here, we investigated whether TSG-6 express...

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Detalles Bibliográficos
Autores principales: Gong, Seong Chan, Yoon, Yongdae, Jung, Pil Young, Kim, Moon Young, Baik, Soon Koo, Ryu, Hoon, Eom, Young Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656625/
https://www.ncbi.nlm.nih.gov/pubmed/36361907
http://dx.doi.org/10.3390/ijms232113122