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Multiplexed Imaging Reveals the Spatial Relationship of the Extracellular Acidity-Targeting pHLIP with Necrosis, Hypoxia, and the Integrin-Targeting cRGD Peptide

pH (low) insertion peptides (pHLIPs) have been developed for cancer imaging and therapy targeting the acidic extracellular microenvironment. However, the characteristics of intratumoral distribution (ITD) of pHLIPs are not yet fully understood. This study aimed to reveal the details of the ITD of pH...

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Detalles Bibliográficos
Autores principales: Jin, Zhao-Hui, Tsuji, Atsushi B., Degardin, Mélissa, Dumy, Pascal, Boturyn, Didier, Higashi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656628/
https://www.ncbi.nlm.nih.gov/pubmed/36359894
http://dx.doi.org/10.3390/cells11213499