Antagonization of OX(1) Receptor Potentiates CB(2) Receptor Function in Microglia from APP(Sw/Ind) Mice Model

Microdialysis assays demonstrated a possible role of orexin in the regulation of amyloid beta peptide (Aß) levels in the hippocampal interstitial fluid in the APP transgenic model. CB(2)R is overexpressed in activated microglia, showing a neuroprotective effect. These two receptors may interact, for...

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Detalles Bibliográficos
Autores principales: Raïch, Iu, Rebassa, Joan Biel, Lillo, Jaume, Cordomi, Arnau, Rivas-Santisteban, Rafael, Lillo, Alejandro, Reyes-Resina, Irene, Franco, Rafael, Navarro, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656664/
https://www.ncbi.nlm.nih.gov/pubmed/36361598
http://dx.doi.org/10.3390/ijms232112801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656664/
https://www.ncbi.nlm.nih.gov/pubmed/36361598
http://dx.doi.org/10.3390/ijms232112801

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