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Hypusinated eIF5A Promotes Ribosomal Frameshifting during Decoding of ODC Antizyme mRNA in Saccharomyces cerevisiae

Polyamines are essential biogenic poly-cations with important roles in many cellular processes and diseases such as cancer. A rate-limiting step early in the biosynthesis of polyamines is the conversion of ornithine to putrescine by the homodimeric enzyme ornithine decarboxylase (ODC). In a conserve...

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Detalles Bibliográficos
Autores principales: Halwas, Kai, Döring, Lennard-Maximilian, Oehlert, Franziska Valentina, Dohmen, R. Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656687/
https://www.ncbi.nlm.nih.gov/pubmed/36361762
http://dx.doi.org/10.3390/ijms232112972