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Synthesis and Biological Activity of N-acyl Anabasine and Cytisine Derivatives with Adamantane, Pyridine and 1,2-Azole Fragments

A series of N-acyl derivatives of anabasine and cytisine were prepared, to discover novel, natural product-based medicinal agents. All synthesized compounds were tested for antimicrobial, antifungal, antiviral and analgesic activity. The most pronounced antibacterial activity was shown by the compou...

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Detalles Bibliográficos
Autores principales: Mukusheva, Gulim K., Zhasymbekova, Aigerym R., Zhumagalieva, Zharkyn Zh., Seidakhmetova, Roza B., Nurkenov, Oralgazy A., Akishina, Ekaterina A., Petkevich, Sergey K., Dikusar, Evgenij A., Potkin, Vladimir I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656753/
https://www.ncbi.nlm.nih.gov/pubmed/36364219
http://dx.doi.org/10.3390/molecules27217387