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Trichostatin D as a Novel KLF2 Activator Attenuates TNFα-Induced Endothelial Inflammation

Krüppel-like factor 2 (KLF2) is an atherosclerotic protective transcription factor that maintains endothelial cell homeostasis through its anti-inflammatory, anti-oxidant, and antithrombotic properties. The aim of this study was to discover KLF2 activators from microbial secondary metabolites and ex...

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Detalles Bibliográficos
Autores principales: Lei, Lijuan, Chen, Minghua, Wang, Chenyin, Jiang, Xinhai, Li, Yinghong, Wang, Weizhi, Li, Shunwang, Zhao, Liping, Sheng, Ren, Han, Jiangxue, Zhang, Yuyan, Chen, Yuchuan, Yan, Biying, Wu, Yexiang, Yu, Liyan, Si, Shuyi, Xu, Yanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656815/
https://www.ncbi.nlm.nih.gov/pubmed/36362263
http://dx.doi.org/10.3390/ijms232113477