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High-Resolution Crystal Structure of Muscle Phosphoglycerate Mutase Provides Insight into Its Nuclear Import and Role

Phosphoglycerate mutase (PGAM) is a glycolytic enzyme converting 3-phosphoglycerate to 2-phosphoglycerate, which in mammalian cells is expressed in two isoforms: brain (PGAM1) and muscle (PGAM2). Recently, it was shown that besides its enzymatic function, PGAM2 can be imported to the cell nucleus wh...

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Detalles Bibliográficos
Autores principales: Wiśniewski, Janusz, Barciszewski, Jakub, Turlik, Jakub, Baran, Karolina, Duda, Przemysław, Jaskolski, Mariusz, Rakus, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656839/
https://www.ncbi.nlm.nih.gov/pubmed/36361985
http://dx.doi.org/10.3390/ijms232113198