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High-Resolution Crystal Structure of Muscle Phosphoglycerate Mutase Provides Insight into Its Nuclear Import and Role
Phosphoglycerate mutase (PGAM) is a glycolytic enzyme converting 3-phosphoglycerate to 2-phosphoglycerate, which in mammalian cells is expressed in two isoforms: brain (PGAM1) and muscle (PGAM2). Recently, it was shown that besides its enzymatic function, PGAM2 can be imported to the cell nucleus wh...
Autores principales: | Wiśniewski, Janusz, Barciszewski, Jakub, Turlik, Jakub, Baran, Karolina, Duda, Przemysław, Jaskolski, Mariusz, Rakus, Dariusz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656839/ https://www.ncbi.nlm.nih.gov/pubmed/36361985 http://dx.doi.org/10.3390/ijms232113198 |
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