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Elevated ETV6 Expression in Glioma Promotes an Aggressive In Vitro Phenotype Associated with Shorter Patient Survival

Background: GBM astrocytes may adopt fetal astrocyte transcriptomic signatures involved in brain development and migration programs to facilitate diffuse tumor infiltration. Our previous data show that ETS variant 6 (ETV6) is highly expressed in human GBM and fetal astrocytes compared to normal matu...

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Detalles Bibliográficos
Autores principales: Xiong, Zhang, Wu, Shuai, Li, Feng-jiao, Luo, Chen, Jin, Qiu-yan, Connolly, Ian David, Hayden Gephart, Melanie, You, Linya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656946/
https://www.ncbi.nlm.nih.gov/pubmed/36292767
http://dx.doi.org/10.3390/genes13101882