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Development and Validation of a UHPLC–MS/MS-Based Method to Quantify Cenobamate in Human Plasma Samples

Cenobamate (CNB) is the newest antiseizure medication (ASM) approved by the FDA in 2019 to reduce uncontrolled partial-onset seizures in adult patients. Marketed as Xcopri in the USA or Ontozry in the EU (tablets), its mechanism of action has not been fully understood yet; however, it is known that...

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Detalles Bibliográficos
Autores principales: Charlier, Bruno, Coglianese, Albino, Operto, Francesca Felicia, Coppola, Giangennaro, de Grazia, Ugo, Menna, Pierantonio, Filippelli, Amelia, Dal Piaz, Fabrizio, Izzo, Viviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656984/
https://www.ncbi.nlm.nih.gov/pubmed/36364153
http://dx.doi.org/10.3390/molecules27217325