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Thermal and Structural Characterization of Two Crystalline Polymorphs of Tafamidis Free Acid

Tafamidis, chemical formula C(14)H(7)Cl(2)NO(3), is a drug used to delay disease progression in adults suffering from transthyretin amyloidosis, and is marketed worldwide under different tradenames as a free acid or in the form of its meglumine salt. The free acid (CAS no. 594839-88-0) is reported t...

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Detalles Bibliográficos
Autores principales: Masciocchi, Norberto, Abbinante, Vincenzo Mirco, Zambra, Marco, Barreca, Giuseppe, Zampieri, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656987/
https://www.ncbi.nlm.nih.gov/pubmed/36364244
http://dx.doi.org/10.3390/molecules27217411