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The Role of Hippo Signaling Pathway and ILK in the Pathophysiology of Human Hypertrophic Scars and Keloids: An Immunohistochemical Investigation

Background: Keloids and hypertrophic scars are characterized by abnormal fibroblast activation and proliferation. While their molecular pathogenesis remains unclear, myofibroblasts have been associated with their development. Hippo pathway effectors YAP/TAZ promote cell proliferation and matrix stif...

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Detalles Bibliográficos
Autores principales: Petrou, Ilias G., Nikou, Sofia, Madduri, Srinivas, Nifora, Martha, Bravou, Vasiliki, Kalbermatten, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657014/
https://www.ncbi.nlm.nih.gov/pubmed/36359821
http://dx.doi.org/10.3390/cells11213426