Different Requirements of CBFB and RUNX2 in Skeletal Development among Calvaria, Limbs, Vertebrae and Ribs

RUNX proteins, such as RUNX2, regulate the proliferation and differentiation of chondrocytes and osteoblasts. Haploinsufficiency of RUNX2 causes cleidocranial dysplasia, but a detailed analysis of Runx2(+/−) mice has not been reported. Furthermore, CBFB is required for the stability and DNA binding...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Qing, Qin, Xin, Nagano, Kenichi, Komori, Hisato, Matsuo, Yuki, Taniuchi, Ichiro, Ito, Kosei, Komori, Toshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657020/
https://www.ncbi.nlm.nih.gov/pubmed/36362086
http://dx.doi.org/10.3390/ijms232113299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657020/
https://www.ncbi.nlm.nih.gov/pubmed/36362086
http://dx.doi.org/10.3390/ijms232113299

Ejemplares similares