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Valdecoxib Protects against Cell Apoptosis Induced by Endoplasmic Reticulum Stress via the Inhibition of PERK-ATF4-CHOP Pathway in Experimental Glaucoma

The purpose of this study was to investigate the effects of valdecoxib on the retina in retinal ischemia-reperfusion injury (IRI) and R28 cells following oxygen-glucose deprivation/recovery (OGD/R) injury, as well as the underlying mechanisms. Immunofluorescence and Cell Counting Kit-8 (CCK-8) analy...

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Detalles Bibliográficos
Autores principales: Gao, Zhaolin, Li, Min, Yao, Fei, Xia, Xiaobo, Duan, Tianqi, Meng, Jingzhuo, Huang, Yanxia, He, Ye, Saro, Adonira, Huang, Jufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657191/
https://www.ncbi.nlm.nih.gov/pubmed/36361772
http://dx.doi.org/10.3390/ijms232112983