Inhibition of LIFR Blocks Adiposity-Driven Endometrioid Endometrial Cancer Growth

SIMPLE SUMMARY: In this study, we utilized global RNA-seq to elucidate the molecular mechanisms by which obese conditions promote progression of endometrioid endometrial cancer (EEC). Our results suggest that obese conditions upregulate LIF/LIFR signaling, and EEC tumors collected from obese patient...

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Detalles Bibliográficos
Autores principales: Blankenship, Logan, Pratap, Uday P., Yang, Xue, Liu, Zexuan, Altwegg, Kristin A., Santhamma, Bindu, Ramasamy, Kumaraguruparan, Konda, Swapna, Chen, Yidong, Lai, Zhao, Zheng, Siyuan, Sareddy, Gangadhara R., Valente, Philip T., Kost, Edward R., Nair, Hareesh B., Tekmal, Rajeshwar R., Vadlamudi, Ratna K., Viswanadhapalli, Suryavathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657203/
https://www.ncbi.nlm.nih.gov/pubmed/36358818
http://dx.doi.org/10.3390/cancers14215400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657203/
https://www.ncbi.nlm.nih.gov/pubmed/36358818
http://dx.doi.org/10.3390/cancers14215400

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