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Contribution of Microhomology to Genome Instability: Connection between DNA Repair and Replication Stress
Microhomology-mediated end joining (MMEJ) is a highly mutagenic pathway to repair double-strand breaks (DSBs). MMEJ was thought to be a backup pathway of homologous recombination (HR) and canonical nonhomologous end joining (C-NHEJ). However, it attracts more attention in cancer research due to its...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657218/ https://www.ncbi.nlm.nih.gov/pubmed/36361724 http://dx.doi.org/10.3390/ijms232112937 |