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Dark Sweet Cherry (Prunus avium) Anthocyanins Suppressed ERK1/2-Akt/mTOR Cell Signaling and Oxidative Stress: Implications for TNBC Growth and Invasion

This study aimed to assess dark sweet cherry (DSC) total polyphenols (WE) and anthocyanins (ACN) against metastatic breast cancer (BC). The WE and ACN anticancer activity and underlying mechanisms were assessed in vitro using 4T1 BC cells. A pilot study using a BALB/C mouse syngeneic model bearing 4...

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Detalles Bibliográficos
Autores principales: Silveira Rabelo, Ana Carolina, Mertens-Talcott, Susanne U., Chew, Boon P., Noratto, Giuliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657292/
https://www.ncbi.nlm.nih.gov/pubmed/36364072
http://dx.doi.org/10.3390/molecules27217245