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α-Bisabolol Attenuates NF-κB/MAPK Signaling Activation and ER-Stress-Mediated Apoptosis by Invoking Nrf2-Mediated Antioxidant Defense Systems against Doxorubicin-Induced Testicular Toxicity in Rats

The present study investigated the effects of α-bisabolol on DOX-induced testicular damage in rats. Testicular damage was induced in rats by injecting DOX (12.5 mg/kg, i.p., single dose) into rats. α-Bisabolol (25 mg/kg, i.p.) was administered to the rats along with DOX pre- and co-treatment daily f...

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Detalles Bibliográficos
Autores principales: Arunachalam, Seenipandi, Nagoor Meeran, Mohamed Fizur, Azimullah, Sheikh, Kumar Jha, Niraj, Saraswathiamma, Dhanya, Albawardi, Alia, Beiram, Rami, Ojha, Shreesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657294/
https://www.ncbi.nlm.nih.gov/pubmed/36364909
http://dx.doi.org/10.3390/nu14214648