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Targeting SPHK1/PBX1 Axis Induced Cell Cycle Arrest in Non-Small Cell Lung Cancer

Non-small cell lung cancer (NSCLC) accounts for 85~90% of lung cancer cases, with a poor prognosis and a low 5-year survival rate. Sphingosine kinase-1 (SPHK1), a key enzyme in regulating sphingolipid metabolism, has been reported to be involved in the development of NSCLC, although the underlying m...

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Detalles Bibliográficos
Autores principales: Lin, Zhoujun, Li, Yin, Han, Xiao, Fu, Zhenkun, Tian, Zhenhuan, Li, Chenggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657307/
https://www.ncbi.nlm.nih.gov/pubmed/36361531
http://dx.doi.org/10.3390/ijms232112741