Identification of Boronate-Containing Diarylpyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

In this study, privileged boronic acid ester was introduced into the right wing of etravirine (ETR) to obtain a series of novel boronate-containing derivatives. These newly synthesized derivatives were evaluated for their anti-HIV potency in MT-4 cells using the MTT method, and their inhibitory acti...

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Detalles Bibliográficos
Autores principales: Feng, Da, Lin, Hao, Jiang, Liyang, Wang, Zhao, Sun, Yanying, Zhou, Zhongxia, Clercq, Erik De, Pannecouque, Christophe, Kang, Dongwei, Zhan, Peng, Liu, Xinyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657321/
https://www.ncbi.nlm.nih.gov/pubmed/36364360
http://dx.doi.org/10.3390/molecules27217538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657321/
https://www.ncbi.nlm.nih.gov/pubmed/36364360
http://dx.doi.org/10.3390/molecules27217538

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