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Lamp1 Deficiency Enhances Sensitivity to α-Synuclein and Oxidative Stress in Drosophila Models of Parkinson Disease

Parkinson disease (PD) is a common neurodegenerative condition affecting people predominantly at old age that is characterized by a progressive loss of midbrain dopaminergic neurons and by the accumulation of α-synuclein-containing intraneuronal inclusions known as Lewy bodies. Defects in cellular d...

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Detalles Bibliográficos
Autores principales: Rahmani, Zohra, Surabhi, Satya, Rojo-Cortés, Francisca, Dulac, Amina, Jenny, Andreas, Birman, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657416/
https://www.ncbi.nlm.nih.gov/pubmed/36361864
http://dx.doi.org/10.3390/ijms232113078